The Nirenberg and Leder experiment was a scientific experiment performed in 1964 by Marshall W. Nirenberg and Philip Leder. The experiment elucidated the triplet nature of the genetic code and allowed the remaining ambiguities codons in the genetic code to be deciphered.
In this experiment, using a ribosome binding assay, various combinations of mRNA were passed through a filter which contained ribosomes. Unique triplets promoted the binding of specific tRNAs to the ribosome. By associating the tRNA with its specific amino acid, it was possible to determine the triplet mRNA sequence that coded for each amino acid.
Read more about Nirenberg And Leder Experiment: Background, Experimental Work, Reception and Legacy
Famous quotes containing the words leder and/or experiment:
“Whether changes in the sibling relationship during adolescence create long-term rifts that spill over into adulthood depends upon the ability of brothers and sisters to constantly redefine their connection. Siblings either learn to accept one another as independent individuals with their own sets of values and behaviors or cling to the shadow of the brother and sister they once knew.”
—Jane Mersky Leder (20th century)
“The man who invented Eskimo Pie made a million dollars, so one is told, but E.E. Cummings, whose verse has been appearing off and on for three years now, and whose experiments should not be more appalling to those interested in poetry than the experiment of surrounding ice-cream with a layer of chocolate was to those interested in soda fountains, has hardly made a dent in the doughy minds of our so-called poetry lovers.”
—John Dos Passos (1896–1970)