Nile Blue in Oncology
Derivatives of Nile blue are potential photosensitizers in photodynamic therapy of malignant tumors. These dyes aggregate in the tumor cells, especially in the lipid membranes, and/or are sequestered and concentrated in subcellular organelles.
With the Nile blue derivative N-Ethyl-Nile Blue (EtNBA), normal and premalignant tissues in animal experiments can be distinguished by fluorescence spectroscopy in fluorescence imaging. EtNBA shows no phototoxic effects.
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Famous quotes containing the words nile and/or blue:
“Hard by the lilied Nile I saw
A duskish river dragon stretched along.
The brown habergeon of his limbs enamelled
With sanguine alamandines and rainy pearl:
And on his back there lay a young one sleeping,
No bigger than a mouse;”
—Thomas Lovell Beddoes (1803–1849)
“And nothing I cared, at my sky blue trades, that time allows
In all his tuneful turning so few and such morning songs
Before the children green and golden
Follow him out of grace.”
—Dylan Thomas (1914–1953)