Nile Blue in Oncology
Derivatives of Nile blue are potential photosensitizers in photodynamic therapy of malignant tumors. These dyes aggregate in the tumor cells, especially in the lipid membranes, and/or are sequestered and concentrated in subcellular organelles.
With the Nile blue derivative N-Ethyl-Nile Blue (EtNBA), normal and premalignant tissues in animal experiments can be distinguished by fluorescence spectroscopy in fluorescence imaging. EtNBA shows no phototoxic effects.
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Famous quotes containing the words nile and/or blue:
“Hard by the lilied Nile I saw
A duskish river dragon stretched along.
The brown habergeon of his limbs enamelled
With sanguine alamandines and rainy pearl:
And on his back there lay a young one sleeping,
No bigger than a mouse;”
—Thomas Lovell Beddoes (1803–1849)
“The Reverend Samuel Peters ... exaggerated the Blue Laws, but they did include “Capital Lawes” providing a death penalty for any child over sixteen who was found guilty of cursing or striking his natural parents; a death penalty for an incorrigible son; a law forbidding smoking except in a room in a private house; another law declaring smoking illegal except on a journey five miles away from home,...”
—Administration for the State of Con, U.S. public relief program (1935-1943)