Nile Blue in Oncology
Derivatives of Nile blue are potential photosensitizers in photodynamic therapy of malignant tumors. These dyes aggregate in the tumor cells, especially in the lipid membranes, and/or are sequestered and concentrated in subcellular organelles.
With the Nile blue derivative N-Ethyl-Nile Blue (EtNBA), normal and premalignant tissues in animal experiments can be distinguished by fluorescence spectroscopy in fluorescence imaging. EtNBA shows no phototoxic effects.
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Famous quotes containing the words nile and/or blue:
“Hard by the lilied Nile I saw
A duskish river dragon stretched along.
The brown habergeon of his limbs enamelled
With sanguine alamandines and rainy pearl:
And on his back there lay a young one sleeping,
No bigger than a mouse;”
—Thomas Lovell Beddoes (1803–1849)
“True variety is in that plenitude of real and unexpected elements, in the branch charged with blue flowers thrusting itself, against all expectations, from the springtime hedge which seems already too full, while the purely formal imitation of variety ... is but void and uniformity, that is, that which is most opposed to variety....”
—Marcel Proust (1871–1922)