Nile Blue in DNA Electrophoresis
Nile blue is also apparently used in a variety of commercial DNA staining formulations used for DNA electrophoresis. As it does not require UV trans-illumination in order to be visualised in an agarose gel as with ethidium bromide, it can be used to observe DNA as it is separated and also as a dye to aid in gel-extraction of DNA fragments without incurring damage by UV-irradiation.
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Famous quotes containing the words nile, blue and/or dna:
“Hard by the lilied Nile I saw
A duskish river dragon stretched along.
The brown habergeon of his limbs enamelled
With sanguine alamandines and rainy pearl:
And on his back there lay a young one sleeping,
No bigger than a mouse;”
—Thomas Lovell Beddoes (1803–1849)
“When the inhabitants of some sequestered island first descry the “big canoe” of the European rolling through the blue waters towards their shores, they rush down to the beach in crowds, and with open arms stand ready to embrace the strangers. Fatal embrace! They fold to their bosoms the vipers whose sting is destined to poison all their joys; and the instinctive feeling of love within their breasts is soon converted into the bitterest hate.”
—Herman Melville (1819–1891)
“Here [in London, history] ... seemed the very fabric of things, as if the city were a single growth of stone and brick, uncounted strata of message and meaning, age upon age, generated over the centuries to the dictates of some now all-but-unreadable DNA of commerce and empire.”
—William Gibson (b. 1948)