Nicolau may refer to:
- Nicolau (surname)
- Nicolau Coelho, Portuguese explorer
- Nicolau dos Reis Lobato, East-Timorese politician and national hero
- Nicolau Tolentino de Almeida, the foremost Portuguese satirical poet of the 18th century
- Presidente Nicolau Lobato International Airport, airport located in Dili
- Estádio Nicolau Alayon, stadium located in São Paulo
- See also: São Nicolau (disambiguation)