Major Intersections
| County | Location | Mile | km | Destinations | Notes |
|---|---|---|---|---|---|
| Tompkins |
Village of Groton | 0.00 | 0.00 | NY 38 (Main Street / Cayuga Street) | |
| Cortland |
Cortlandville | 9.17 | 14.76 | NY 281 (West Road) | |
| Cortland | 10.43 | 16.79 | US 11 north / NY 41 north (Main Street) | Western terminus of US 11 / NY 41 / NY 222 overlap | |
| 10.57 | 17.01 | US 11 south / NY 13 / NY 41 south (Clinton Avenue) | Eastern terminus of US 11 / NY 41 / NY 222 overlap |
Read more about this topic: New York State Route 222
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