Diseases
Any disorder that compromises the synaptic transmission between a motor neuron and a muscle cell is categorized under the umbrella term neuromuscular diseases. These disorders can be inherited or acquired. These disorders vary in their severity and their mortality. In general, most tend to be caused by mutations or autoimmune disorders. Autoimmune disorders, in the case of neuromuscular diseases, tend to be humoral mediated, B cell mediated, and result in an antibody against a motor neuron or muscle fiber protein that interferes with synaptic transmission or signaling.
Read more about this topic: Neuromuscular Junction
Famous quotes containing the word diseases:
“Arrogance, pedantry, and dogmatism ... the occupational diseases of those who spend their lives directing the intellects of the young.”
—Henry S. Canby (1878–1961)
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—Louis-Ferdinand Céline (1894–1961)
“A fiction about soft or easy deaths ... is part of the mythology of most diseases that are not considered shameful or demeaning.”
—Susan Sontag (b. 1933)