Prevention
Magnesium deficiency causes neurogenic inflammation in a rat model. Researchers have theorized that since substance P which appears at day five of induced magnesium deficiency, is known to stimulate in turn the production of other inflammatory cytokines including IL-1, IL-6, and TNF-alpha, which begin a sharp rise at day 12, substance P is a key in the path from magnesium deficiency to the subsequent cascade of neuro-inflammation. In a later study, researchers observed bone loss in rats that received reduced levels of dietary magnesium, but within the range of dietary intake found in the human population. Even that marginal magnesium deficiency was found to result in an increase in substance P, TNFalpha, and IL1beta. These and other data support the notion that deficient dietary magnesium intake, even at levels not uncommon in humans, not only triggers neurogenic inflammation but may also be a risk factor for osteoporosis.
Read more about this topic: Neurogenic Inflammation
Famous quotes containing the word prevention:
“... if this world were anything near what it should be there would be no more need of a Book Week than there would be a of a Society for the Prevention of Cruelty to Children.”
—Dorothy Parker (1893–1967)