Neoplastic Meningitis - Symptoms

Symptoms

3 affected domains of neurological function:

  • cerebral hemisphere (15%)
  • Cranial Nerves (35%)
  • Spinal cord and roots (60%)

Signs reported

  • headache
  • mental status change
  • confusion
  • cognitive impairment
  • seizures
  • hemiparesis
  • gait instability

Other symptoms that are less common are dementia, autonomic dysfunction, cranial nerve abnormalities, spinal symptoms such as limb weakness and paresthesia, and bowel and bladder dysfunction. Diplopia is the most common symptom of cranial nerve dysfunction. Trigeminal sensory or motor loss, cochlear dysfunction, and optic neuropathy are also common findings. Spinal signs and symptoms include weakness, dermatomal or segmental sensory loss, and pain in the neck, back, or following radicular patterns.

Read more about this topic:  Neoplastic Meningitis

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