Diagnosis
Maternal and paternal platelet antigen phenotyping and screening of the maternal serum for anti-platelet antibodies can be performed.
Additionally, platelet antigen genotyping can be performed on the maternal and paternal blood to determine the exact nature of the incompatibility.
Neonatal platelet counts on laboratory testing are typically under 20,000/uL. Higher counts may suggest a different diagnosis, such as maternal immune thrombocytopenic purpura (ITP).
Read more about this topic: Neonatal Alloimmune Thrombocytopenia