NGP By Heteroatom Lone Pairs
A classic example of NGP is the reaction of a sulfur or nitrogen mustard with a nucleophile, the rate of reaction is much higher for the sulfur mustard and a nucleophile than it would be for a primary alkyl chloride without a heteroatom.
In sugar chemistry anchimeric assistance is an example of NGP.
Read more about this topic: Neighbouring Group Participation
Famous quotes containing the word lone:
“In the lowlands I have no comrade, not even the lone mans friend”
—Thomas Hardy (18401928)