National Institute of General Medical Sciences - Research Advances

Research Advances

Among the advances that scientists have made with NIGMS support are:

  • Discovering a gene-silencing process called RNA interference, or RNAi, that is both a powerful research tool and a promising new approach for treating diseases.
  • Revealing how a protein's shape affects its function, which plays a key role in health and disease and also informs the design of new drugs.
  • Increasing survival from burn injury, in part by improving methods of wound care, nutrition and infection control.
  • Explaining how genes affect the way a person responds to drugs, including those to treat cancer and prevent blood clots.
  • Shedding light on the critical functions of carbohydrates, sugar molecules found on all living cells that are vital to fertilization, inflammation, blood clotting and viral infection.
  • Modeling infectious disease outbreaks and the impact of interventions through computer simulations to provide valuable information to public health policymakers.
  • Developing new methods to look inside cells and other living systems. These approaches have advanced what we know about basic life processes in a range of organisms.

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