Nadel, which means needle in German, is a surname that may refer to:
- Barbara Nadel, an English crime-writer, and previous winner of the CWA Silver Dagger
- Eric Nadel (b. 1951), a sports announcer on radio broadcasts for the Texas Rangers baseball organization
- Siegfried Frederick Nadel (1903-1956), an Austrian-born British anthropologist, specialising in African ethnology
- Arthur Nadel (born 1932), hedge fund manager accused of $350 million fraud