Differences in Presentation
As noted, all types of MEN2 include pheochromocytoma, and medullary thyroid carcinoma.
MEN2A is additionally characterized by the presence of parathyroid hyperplasia or tumor.
MEN2B is additionally characterized by the presence of mucocutaneous neuroma, gastrointestinal symptoms (e.g. constipation and flatulence), and muscular hypotonia.
MEN2B can present with a Marfanoid habitus.
Read more about this topic: Multiple Endocrine Neoplasia Type 2
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