Assumptions
Multi-compartment modeling requires the adoption of several assumptions, such that systems in physical existence can be modeled mathematically:
- Instant homogeneous distribution of materials or energies within a "compartment."
- The exchange rate of materials or energies among the compartments is related to the densities of these compartments.
- Usually, it is desirable that the materials do not undergo chemical reactions while transmitting among the compartments.
- When concentration of the cell is of interest, typically the volume is assumed to be constant over time, though this may not be totally true in reality.
Most commonly, the mathematics of multi-compartment models is simplified to provide only a single parameter--such as concentration--within a compartment.
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