Muller Glia - Role in Development

Role in Development

Müller glia have been shown to be critical to the development of the retina in mice, serving as promoters of retinal growth and histogenesis via a non-specific esterase mediated mechanism. Müller glia have also been implicated to serve as guidepost cells for the developing axons of neurons in the chick retina. Studies using a zebrafish model of Usher syndrome have implicated a role for Müller glia in synaptogenesis, the formation of synapses.

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