Molecular Biology
Mucoepidermoid carcinomas of the salivary and bronchial glands are characterized by a recurrent t(11;19)(q21;p13) chromosomal translocation resulting in a MECT1-MAML2 fusion gene. The CREB-binding domain of the CREB coactivator MECT1 (also known as CRTC1, TORC1 or WAMTP1) is fused to the transactivation domain of the Notch coactivator MAML2 PMID 16444749.
A possible association with papillomavirus has been reported.
Read more about this topic: Mucoepidermoid Carcinoma
Famous quotes containing the word biology:
“The “control of nature” is a phrase conceived in arrogance, born of the Neanderthal age of biology and the convenience of man.”
—Rachel Carson (1907–1964)