Mother Brain may refer to the following fictional characters:
- Mother Brain (Metroid), a main antagonist in the Metroid video game series, and the crossover fiction Captain N: The Game Master cartoon show based on it
- A character in the video game Chrono Trigger
- A character in the video game Phantasy Star II
- A character in the video game I Wanna Be The Guy
Famous quotes containing the word mother:
“My mother said that I never should
Play with the gypsies in the wood,”
—Unknown. Gypsies in the Wood (l. 1–2)