Examples
- Histamine (His/H is Diamine)
- Catecholamines:
- Dopamine (DA)
- Noradrenaline (NA) (Norepinephrine, NE)
- Adrenaline (Epinephrine)
- Tryptamines:
- Serotonin (5-HT)
- Melatonin
- Trace amines:
- β-Phenylethylamine (PEA, β-PEA)
- Tyramine
- Tryptamine
- Octopamine
- 3-Iodothyronamine
- Thyronamines, a new group of compounds derived from thyroid hormones
Specific transporter proteins called monoamine transporters that transport monoamines in or out of a cell exist. These are the dopamine transporter (DAT), serotonin transporter (SERT), and the norepinephrine transporter (NET) in the outer cell membrane and the vesicular monoamine transporter (VMAT1 and VMAT2) in the membrane of intracellular vesicles.
After release into the synaptic cleft, monoamine neurotransmitter action is ended by reuptake into the presynaptic terminal. There, they can be repackaged into synaptic vesicles or degraded by the enzyme monoamine oxidase (MAO), which is a target of monoamine oxidase inhibitors, a class of antidepressants.
Read more about this topic: Monoamine Neurotransmitter
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