Moist Heat Sterilization - Action On Micro-organisms

Action On Micro-organisms

Moist heat causes destruction of micro-organisms by denaturation of macromolecules, primarily proteins. Destruction of cells by lysis may also play a role. While "sterility" implies the destruction of free-living organisms which may grow within a sample, sterilisation does not necessarily entail destruction of infectious matter. Prions are an example of an infectious agent that can survive sterilisation by moist heat, depending on conditions.

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