MNC may refer to:
- Media Nusantara Citra, Indonesian media company and owner of RCTI, MNC TV, Sun TV, and Indovision
- MNC The Indonesian Channel
- Mobile Network Code
- Monday Night Combat, a video game for the Xbox 360 and PC
- Monocyte
- Multinational corporation
- Museo Nacional de las Culturas, a museum in Mexico City, Mexico
- Mythical national championship