Targets
A number of targets for microRNA-21 have been experimentally validated and most of them are tumor suppressors. Notable targets include PTEN, PDCD4, Tropomyosin, Sprouty 1, Sprouty 2, Bcl2, RECK, IL-12p35, JAG1, HNRPK, BTG2, TGFBRII, TAp63, P12/CDK2AP1, MEF2C, ANP32A, SMARCA4, RhoB, and hMSH2.
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