Expression Patterns
miR-129 seems to have a tissue specific expression pattern localised to the brain in normal humans. This finding was identified initially by microarray experimentation with mouse tissue (and more specifically to the cerebellum) which was subsequently validated by the expression profiling in human tissue. However, expression in normal brain tissue was found to be relatively low and different profiling experimentation methodologies produced differing results. These differences and the low levels of detection may be attributed to the size and complexity of the human brain and the fact that specific regions of the brain were not individually tested.
Read more about this topic: Mir-129 Micro RNA Precursor Family
Famous quotes containing the words expression and/or patterns:
“While I shall not vote for the prohibition amendment, I would like to see a good, wholesome expression of temperance sentiment.... Personally I do not resort to force—not even the force of law—to advance moral reforms. I prefer education, argument, persuasion, and above all the influence of example—of fashion.”
—Rutherford Birchard Hayes (1822–1893)
“The ninety percent of human experience that does not fit into established narrative patterns falls into oblivion.”
—Mason Cooley (b. 1927)