Mimosa Tenuiflora - Entheogenic Uses

Entheogenic Uses

Mimosa tenuiflora is an entheogen known as Jurema, Jurema Preta, Black Jurema, and Vinho de Jurema. Dried Mexican Mimosa tenuiflora root bark has been recently shown to have a DMT (Dimethyltryptamine) content of about 1%. The stem bark has about 0.03% DMT. The bark is the part of the tree traditionally used in northeastern Brazil in a psychoactive decoction also called Jurema or Yurema. Analogously, the traditional Western Amazonian sacrament Ayahuasca is brewed from indigenous ayahuasca vines. However, to date no β-carbolines such as harmala alkaloids have been detected in Mimosa tenuiflora decoctions, yet the root bark is consistently used without added MAOI.

This presents challenges to the pharmacological understanding of how DMT from the plant is rendered orally active as an entheogen. In this view, if MAOI is neither present in the plant nor added to the mixture, the enzyme MAO will break apart DMT in the human gut, preventing the active molecule from entering blood and brain.

The isolation of a new compound "Yuremamine" Mimosa tenuiflora as reported in 2005 represents a new class of phyto-indoles, which may explain an apparent oral activity of DMT in Jurema.