Microtubule Organizing Center - Spindle Pole Body

Spindle Pole Body

In yeasts and some algae, the MTOC is embedded into the nuclear envelope as a spindle pole body. Centrioles do not exist in the MTOCs of yeast and fungi. In these organisms, the nuclear envelope does not break down during mitosis and the spindle pole body serves to connect cytoplasmic with nuclear microtubules. The disc-shaped spindle pole body is organized into three layers: the central plaque, inner plaque, and outer plaque. The central plaque is embedded in the membrane, while the inner plaque is an amorphous intranuclear layer, and the outer plaque is the layer located in the cytoplasm.

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