Organization of MTOC in Cells
Microtubule-organizing centers function as the site where microtubule formation begin, as well as a location where free-ends of microtubules attract to. Within the cells, microtubule-organizing centers can take on many different forms. An array of microtubules can arrange themselves in a pinwheel structure to form the basal bodies, which can lead to the formation of microtubule arrays in the cytoplasm or the 9+2 axoneme. Other arrangements range from fungi spindle pole bodies to the eukaryotic chromosal kinetochores (flat, laminated plaques). MTOCs can be freely dispersed throughout the cytoplasm or centrally localized as foci. The most notable MTOCs are the centrosome at interphase and the mitotic spindle poles.
Centrioles can act as markers for MTOCs in the cell. If they are freely distributed in the cytoplasm, centrioles can gather during differentiation to become MTOCs. They can also be focused around a centrosome as a single MTOC, though centrosomes can work as an MTOC absent of centrioles.
Read more about this topic: Microtubule Organizing Center
Famous quotes containing the words organization of, organization and/or cells:
“Politics, as a practise, whatever its professions, has always been the systematic organization of hatreds.”
—Henry Brooks Adams (1838–1918)
“The art of government is the organization of idolatry. The bureaucracy consists of functionaries; the aristocracy, of idols; the democracy, of idolaters. The populace cannot understand the bureaucracy: it can only worship the national idols.”
—George Bernard Shaw (1856–1950)
“Madness is locked beneath. It goes into tissues, is swallowed by the cells. The cells go mad. Cancer is their flag. Cancer is the growth of madness denied.”
—Norman Mailer (b. 1923)