Microscale Chemistry - History

History

There are two main strands of the modern approach. One is based on the idea that many of the experiments associated with General Chemistry (acids and bases, oxidation and reduction, electrochemistry, etc.) can be carried out in equipment much simpler (injection bottles, dropper bottles, syringes, wellplates, plastic pipettes) and therefore cheaper than the traditional glassware in a laboratory, thus enabling the expansion of the laboratory experiences of students in large classes and to introduce laboratory work into institutions too poorly equipped for standard-type work. Pioneering development in this area was carried out by Egerton C. Grey (1928), Mahmoud K. El-Marsafy (1989) in Egypt, Stephen Thompson in the US and others. A further application of these ideas was the devising by Bradley of the Radmaste kits in South Africa, designed to make effective chemical experiments possible in developing countries in schools that lack the technical services (electricity, running water) taken for granted in many places. The other strand is the introduction of this approach into synthetic work, mainly in organic chemistry. Here the crucial breakthrough was achieved by Mayo, Pike and Butcher and by Williamson who demonstrated that inexperienced students were able to carry out organic syntheses on a few tens of milligrams, a skill previously thought to require years of training and experience. These approaches were accompanied by the introduction of some specialised equipment, which was subsequently simplified by Breuer without great loss of versatility.

There is a great deal of published material available to help in the introduction of such a scheme, providing advice on choice of equipment, techniques and preparative experiments and the flow of such material is continuing through a column in the Journal of Chemical education called ‘The Microscale Laboratory’ that has been running for many years. Scaling down experiments, when combined with modern projection technology, opened up the possibility of carrying out lecture demonstrations of the most hazardous kind in total safety. The approach has been adopted world wide. It has become a major presence on the educational scene in the US, it is used to a lesser extent in the UK and it is used in many countries in institutions with staff who are enthusiastic about it.

Read more about this topic:  Microscale Chemistry

Famous quotes containing the word history:

    History has neither the venerableness of antiquity, nor the freshness of the modern. It does as if it would go to the beginning of things, which natural history might with reason assume to do; but consider the Universal History, and then tell us,—when did burdock and plantain sprout first?
    Henry David Thoreau (1817–1862)

    Hence poetry is something more philosophic and of graver import than history, since its statements are rather of the nature of universals, whereas those of history are singulars.
    Aristotle (384–322 B.C.)

    All history attests that man has subjected woman to his will, used her as a means to promote his selfish gratification, to minister to his sensual pleasures, to be instrumental in promoting his comfort; but never has he desired to elevate her to that rank she was created to fill. He has done all he could to debase and enslave her mind; and now he looks triumphantly on the ruin he has wrought, and say, the being he has thus deeply injured is his inferior.
    Sarah M. Grimke (1792–1873)