Honors
- Lifetime Achievement Awards from the Academy of Medical Films
- American Heart Association (AHA)
- Children Uniting Nations
- Encyclopædia Britannica
- Foundation for Biomedical Research
- International College of Angiology
- International Health and Medical Film Festival
- Honorary Director of Research!America
- Tulane Medical Alumni Association
- U.S. Army Legion of Merit (1945)
- American Medical Association Hektoen Gold Medal (1954 and 1970)
- Rudolph Matas Award in Vascular Surgery (1954)
- International Society of Surgery Distinguished Service Award (1958)
- Leriche Award (1959)
- American Medical Association Distinguished Service Award (1959)
- Albert Lasker Award for Clinical Medical Research (1963)
- American Medical Association Billings Gold Medal Exhibit Award (1967)
- American Heart Association Gold Heart Award (1968)
- Union of Soviet Socialist Republics Academy of Sciences 50th Anniversary Jubilee Medal (1973)
- Russian Academy of Medical Sciences Foreign Member (1974)
- Veterans of Foreign Wars Commander-in-Chief’s Medal and Citation (1980)
- American Surgical Association Distinguished Service Award (1981)
- Academy of Surgical Research Markowitz Award (1988)
- Association of American Medical Colleges Special Recognition Award (1988)
- Honorary Doctorate of Science from Universidad Francisco Marroquin (1989)
- American Legion Distinguished Service Award (1990)
- Honorary President of the International Society for Rotary Blood Pumps (1992)
- Special Award for Space Technology Utilization (1997)
- Premio Giuseppe Corradi Award for Surgery and Scientific Research (1997)
- Russian Military Medical Academy, Boris Petrovsky International Surgeons Award and First Laureate of the Boris Petrovsky Gold Medal (1997)
- Grau de Grande Oficial da Ordem de Santiago de Espada, Portugal, 1998
- Scientific Achievement Award of The American Association for Thoracic Surgery (1999)
- John P. McGovern Compleat Physician Award (1999)
- Russian Academy of Sciences Foreign Member (1999)
- Texas Senate and House of Representatives, Adoption of resolutions honoring DeBakey for 50 years of medical practice in Texas (1999)
- American Medical Association Virtual Mentor Award (2000)
- American Philosophical Society Jonathan Rhoads Medal (2000)
- Library of Congress Bicentennial Living Legend Award (2000)
- Villanova University Mendel Medal Award (2001)
- Houston Hall of Fame (2001)
- NASA Invention of the Year Award (2001)
- MUSC Lindbergh-Carrel Prize (2002)
- Lomonosov Large Gold Medal, Russian Academy of Sciences (2003)
- Congressional Gold Medal (April 23, 2008)
- First person ever to lie in state in the Houston City Hall Rotunda
- The Denton A. Cooley Leadership Award (January 21, 2009)
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