Mexican Federal Highway 40, also called the "Carretera Interoceánica" (Interoceanic Highway) is a road beginning at Reynosa, Tamaulipas, just west of the Port of Brownsville, Texas, and ending at Mexican Federal Highway 15 in Villa Unión, Sinaloa near Mazatlán and the Pacific coast. It is called Interoceanic as, once finished, the cities of Matamoros, Tamaulipas on the Gulf of Mexico and Mazatlán, Sinaloa at the Pacific Ocean, will be linked.
It passes through Monterrey, Nuevo León, Saltillo, Coahuila, Torreón, Gómez Palacio, and Durango, Durango. The Monterrey to Durango section is a 4-lane divided highway. The rest of the road is a 2-lane undivided road. Parallel to this highway, in some sections, runs Federal Highway 40D, which is a 4-lane restricted access toll road.
The road was also the site of the Cadereyta Jiménez massacre on 13 May 2012.
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