Methylenetetrahydrofolate Reductase - Reaction Schematic and Folate Pathway

Reaction Schematic and Folate Pathway

MTHFR = methylenetetrahydrofolate reductase DHF = dihydrofolate THF = tetrahydrofolate
5,10-methylene-THF =
5,10-methylenetetrahydrofolate
5-methyl-THF =
5-methyltetrahydrofolate
MTR = methionine synthase SAH = S-adenosylhomocysteine
NADPH = reduced form of Nicotinamide adenine dinucleotide phosphate NADP+ = oxidized form of Nicotinamide adenine dinucleotide phosphate SAM = S-Adenosyl methionine TS = thymidylate synthase

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