Clinical Significance
Mutations in the MTR gene have been identified as the underlying cause of methylcobalamin deficiency complementation group G, or methylcobalamin deficiency cblG-type. The consequence of reduced methionine synthase activity is megaloblastic anemia.
Read more about this topic: Methionine Synthase
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“History is the interpretation of the significance that the past has for us.”
—Johan Huizinga (1872–1945)