Neuropathic Pain
Hyperalgesia and allodynia are examples of neuropathic pain. It is thought that the activation of specialized neuronal nociceptors are responsible for hyperalgesia. Studies suggest that hyperalgesia and allodynia are set off and sustained by certain groups of mechanosensitive sensory neurons. There is a general consensus among the scientific community that neuropeptides and NMDA receptors are crucial to the initiation of sensitization states such as hyperalgesia and allodynia.
Read more about this topic: Mechanosensation
Famous quotes containing the word pain:
“Each person is a graveyard of his thoughts. They are most beautiful for us in the moment of their birth; later we can often sense a deep pain that they leave us indifferent where earlier they enchanted us.”
—Robert Musil (1880–1942)