Neuropathic Pain
Hyperalgesia and allodynia are examples of neuropathic pain. It is thought that the activation of specialized neuronal nociceptors are responsible for hyperalgesia. Studies suggest that hyperalgesia and allodynia are set off and sustained by certain groups of mechanosensitive sensory neurons. There is a general consensus among the scientific community that neuropeptides and NMDA receptors are crucial to the initiation of sensitization states such as hyperalgesia and allodynia.
Read more about this topic: Mechanosensation
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“It is manifest therefore that they who have sovereign power, are immediate rulers of the church under Christ, and all others but subordinate to them. If that were not, but kings should command one thing upon pain of death, and priests another upon pain of damnation, it would be impossible that peace and religion should stand together.”
—Thomas Hobbes (1579–1688)