Meca or MECA may refer to:
- Maine College of Art
- Marriage Equality California
- MECA CLUB, students' Mechanical Electrical Civil Architecture group of Ain Shams University Faculty of Engineering, Cairo, Egypt
- mecA, the gene responsible for methicillin resistance in MRSA
- Meca, Kosovo a hamlet in Kosovo
- Meca (moth), a snout moth genus in subfamily Pyralinae
- Mecca, a city in present-day Saudi Arabia
- Mirzapur Ex Cadets Association
- Medical Equipment Compliance Associates
- Mobile Electronics Competition Association
- Maritime E-Commerce Association (MECA)