Mazel may refer to:
- Mazel Group Engineering, a Barcelona based design studio specialising in concept cars and engineering solutions
- People
- Eugène Mazel (1828–1890), French amateur botanist
- Ilya Mazel (aka Ruvim Mazel, 1890–1967), Soviet painter
- Isaak Mazel (1911–1943), Soviet chess master
- Judy Mazel (1943–2007), American weight loss advocate and author of the The Beverly Hills Diet
- Maurice Mazel, prominent Chicago surgeon who founded Edgewater Hospital
- Olivier Mazel (1858–1940), French Army general during World War I
- Zvi Mazel (born 1939), Israeli diplomat