Massaro may refer to:
- Antonio del Massaro, nicknamed il Pastura (1450–1516), Italian painter
- Ashley Massaro (born 1979), American professional wrestler, valet and general manager
- Daniele Massaro (born 1961), former Italian football (soccer) forward
- Domingo Massaro (born 1927), Chileanan football player and referee
- Dominic W. Massaro, Professor of Psychology and Computer Engineering at the University of California, Santa Cruz
- Francesco Massaro (born 1935), Italian director and screenwriter
- John Massaro as Music Director for Blues in the Night with BTT
- John Massaro (guitarist), guitarist for the 1980s band Kid Lightning
- John R. Massaro, USMC retired (born 1930), the 8th Sergeant Major of the Marine Corps (1977–1979)
- Laura Massaro, professional squash player from England
- Mike Massaro, racing analyst at ESPN for the NASCAR Sprint Cup Series
- Paulo Massaro (born 1981), professional association football player
- Roberto Massaro (born 1983), Italian footballer
- Ryan Massaro or Amos Lee (born 1977), American singer-songwriter whose musical style encompasses folk, rock and soul
- Sylvio Massaro, volcalist in Vanishing Point, an Australian power/progressive metal band from Melbourne