Mannich Reaction - Reaction Mechanism

Reaction Mechanism

The mechanism of the Mannich reaction starts with the formation of an iminium ion from the amine and the formaldehyde.

The compound with the carbonyl functional group (in this case a ketone) can tautomerize to the enol form, after which it can attack the iminium ion.

Read more about this topic:  Mannich Reaction

Famous quotes containing the words reaction and/or mechanism:

    The excessive increase of anything often causes a reaction in the opposite direction.
    Plato (c. 427–347 B.C.)

    A mechanism of some kind stands between us and almost every act of our lives.
    Sarah Patton Boyle, U.S. civil rights activist and author. The Desegregated Heart, part 3, ch. 2 (1962)