Mannich Reaction - Reaction Mechanism

Reaction Mechanism

The mechanism of the Mannich reaction starts with the formation of an iminium ion from the amine and the formaldehyde.

The compound with the carbonyl functional group (in this case a ketone) can tautomerize to the enol form, after which it can attack the iminium ion.

Read more about this topic:  Mannich Reaction

Famous quotes containing the words reaction and/or mechanism:

    An actor must communicate his author’s given message—comedy, tragedy, serio- comedy; then comes his unique moment, as he is confronted by the looked-for, yet at times unexpected, reaction of the audience. This split second is his; he is in command of his medium; the effect vanishes into thin air; but that moment has a power all its own and, like power in any form, is stimulating and alluring.
    Eleanor Robson Belmont (1878–1979)

    A mechanism of some kind stands between us and almost every act of our lives.
    Sarah Patton Boyle, U.S. civil rights activist and author. The Desegregated Heart, part 3, ch. 2 (1962)