Mandinka, Mandika, Mandinko or Mandingo may refer to:
- the Mandinka people of West Africa
- the Mandingo people of Sierra Leone
- the Mandinka language
- the Mandinka Empire
- the Mandingo Wars
- Mandingo (novel), a bestselling novel originally published in 1957
- Mandingo (film), a 1975 film based on the novel of the same name
- Mandingo (person), a male African American pornographic performer and director
- "Mandinka" (song), by Sinéad O'Connor from her 1987 album The Lion and the Cobra