Mammary Ductal Carcinoma - Ductal Carcinoma in Situ (intraductal Carcinoma)

Ductal Carcinoma in Situ (intraductal Carcinoma)

Ductal carcinoma in situ (DCIS, also known as intraductal carcinoma) is the most common type of noninvasive breast cancer or pre-cancer in women. Ductal carcinoma refers to the development of cancer cells within the milk ducts of the breast. In situ means "in place" and refers to the fact that the cancer has not moved out of the duct and into any surrounding tissue.

Ductal carcinoma in situ (DCIS) is noninvasive breast cancer that encompasses a wide spectrum of diseases ranging from low-grade lesions that are not life threatening to high-grade lesions that may harbor foci of invasive breast cancer. DCIS has been classified according to architectural pattern (solid, cribriform, papillary, and micropapillary), tumor grade (high, intermediate, and low grade), and the presence or absence of comedo histology.

DCIS almost never produces symptoms or a lump that can be felt, so it is almost always found through screening mammography. As screening mammography has become more widespread, DCIS has become one of the most commonly diagnosed breast conditions, now accounting for 20% of breast cancers and pre-cancers that are detected through screening mammography. DCIS is usually seen on a mammogram as very small specks of calcium known as microcalcifications. However, not all microcalcifications indicate the presence of DCIS, which must be confirmed by biopsy.

Read more about this topic:  Mammary Ductal Carcinoma