Magnetic Resonance Angiography - Clinical Use

Clinical Use

MRA has been successful in studying many arteries in the body, including cerebral and other vessels in the head and neck, the aorta and its major branches in the thorax and abdomen, the renal arteries, and the arteries in the lower limbs. For the coronary arteries, however, MRA has been less successful than CT angiography or invasive catheter angiography. Most often, the underlying disease is atherosclerosis, but medical conditions like aneurysms or abnormal vascular anatomy can also be diagnosed.

An advantage of MRA compared to invasive catheter angiography is the non-invasive character of the examination (no catheters have to be introduced in the body). Another advantage, compared to CT angiography and catheter angiography, is that the patient is not exposed to any ionizing radiation. Also, contrast media used for MRI tend to be less toxic than those used for CT angiography and catheter angiography, with fewer people having any risk of allergy. Also far less is needed to be injected into the patient. The greatest drawbacks of the method are its comparatively high cost and its somewhat limited spatial resolution. The length of time the scans take can also be an issue, with CT being far quicker. It is also ruled out in patients who are unsafe for MRI (such as having a pacemaker or metal in the eyes or certain surgical clips).

MRA procedures for visualizing cranial circulation are no different to the positioning for a normal MRI brain. Immobilization within the head coil will be required. MRA is usually a part of the total MRI brain examination and adds approximately 10 minutes to the normal MRI protocol.

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