Mafa

Mäfä

... MAFA (Mast cell function-associated antigen) is a type II membranal glycoprotein, first identified on the surface of rat mucosal-type mast cells of the RBL-2H3 line ... More recently, human and mouse homologues of MAFA have been discovered yet also (or only) expressed by NK and T-cells ... The intracellular domain of MAFA contains a single immunoreceptor tyrosine-based inhibitory motif (ITIM), which classifies MAFA as a member of an inhibitory receptor superfamily ...