Lymphogranuloma Venereum - Signs and Symptoms

Signs and Symptoms

Lymphogranuloma venereum was described first by Wallace in 1833 and again for Durand, Nicolas, and Favre in 1913. The clinical manifestation of LGV depends on the site of entry of the infectious organism (the sex contact site) and the stage of disease progression.

  • Inoculation at the mucous lining of external sex organs (penis and vagina) can lead to the inguinal syndrome named after the formation of buboes or abscesses in the groin (inguinal) region where draining lymph nodes are located. These signs usually appear by 3 days to a month after exposure.
  • The rectal syndrome arises if the infection takes place via the rectal mucosa (through anal sex) and is mainly characterized by proctocolitis symptoms.
  • The pharyngeal syndrome is rare. It starts after infection of pharyngeal tissue, and buboes in the neck region can occur.

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