Virus Biology
LCMV is an enveloped virus with a helical nucleocapsid containing an RNA genome consisting of two single-stranded RNA segments. The L strand is ambisense RNA and encodes the polymerase and z protein while the S strand is ambisense and encodes the nucleo-protein and glycoproteins. The first arenavirus, lymphocytic choriomeningitis virus (LCMV), was isolated in 1933 by Charles Armstrong during a study of an epidemic in St. Louis. Although not the cause of the outbreak, LCMV was found to be a cause of nonbacterial or aseptic meningitis.
Read more about this topic: Lymphocytic Choriomeningitis
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