Lowrie is a surname and may refer to:
- Allen Lowrie, West Australian botanist
- Donald Lowrie (d.June 5, 1925), American newspaper writer
- George Lowrie (1919-1989), Welsh footballer
- Henry Berry Lowrie (c. 1844 – 1847-disappeared 1872), North Carolina outlaw
- Jason Lowrie, New Zealand rugby league footballer
- Jed Lowrie, infielder for the Houston Astros
- John Patrick Lowrie, American voice actor
- Matthew B. Lowrie (1773-1850), mayor of Pittsburgh, Pennsylvania
- Walter Lowrie (1784–1868), US senator from Pennsylvania
- Walter H. Lowrie, chief justice of Pennsylvania's Supreme Court
- William Lowrie (1857–1933), Australian agricultural educationist