Loftus may refer to:

  • Adam Loftus (Archbishop) (1533–1605), Irish Archbishop, Lord Chancellor of Ireland, first provost of Trinity College, Dublin
  • Adam Loftus, 1st Viscount Loftus (1568–1643), Lord Chancellor of Ireland in 1619
  • Amy Loftus, American singer
  • Cecilia Loftus (1876–1943), Scottish burlesque performer and actress
  • Elizabeth Loftus (born 1944), American psychologist and author
  • John Loftus (born 1950), American author, former US government prosecutor, and former Army intelligence officer
  • Johnny Loftus (1895–1976), American horse racing jockey
  • Loftus Dudley Ward, Canadian naval chief petty officer elected to the Legislative Assembly of Alberta in 1945
  • Loftus William Jones (1879–1916), English recipient of the Victoria Cross
  • Lord Augustus Loftus (Lord Augustus William Frederick Spencer Loftus) (1817–1909), Governor of New South Wales, Australia 1879–1885
  • Robert A. Loftus, Former mayor of Pittstown City, PA
  • Seán Dublin Bay Rockall Loftus (1927–2010), Irish barrister, politician, and environmentalist
  • Thomas Loftus (1917-2011), former Chairman of Leinster Gaelic Athletic Association
  • Tom Loftus (1856–1910), American professional baseball player and manager
  • William Loftus (1820–1858), British geologist, naturalist, explorer, and archaeological excavator
  • Loftus, New South Wales, suburb in Sydney, Australia
  • Loftus, North Yorkshire, town in Redcar and Cleveland, England
  • Loftus Hall, building in County Wexford, Ireland, that is said to have been haunted by the devil
  • Loftus Road, football stadium in London, the home ground of Queens Park Rangers
  • Loftus Versfeld Stadium, Pretoria, South Africa
  • Loftus (band)