Characteristics
Penbutolol is typically administered orally in doses of 20 mg per day . It is rapidly absorbed from the gastrointestinal tract, has a bioavailability over 90%, and has a rapid onset of effect. Penbutolol has a half life of five hours, and a low frequency of side effects . These side effects include dizziness, light headedness, and nausea . When penbutolol is being metabolized, it undergoes a series of biotransformations, the main one being hydroxylation. One potential drawback of penbutolol is the inactivation of β2 adrenergic receptor, which makes this a less than ideal hypertensive treatment for people suffering from asthma or insulin dependent diabetes mellitus.
Read more about this topic: Lobeta