Liver dialysis is a detoxification treatment for liver failure and has shown promise for patients with hepatorenal syndrome. It is similar to hemodialysis and based on the same principles. Like a bioartificial liver device, it is a form of artificial extracorporeal liver support.
A critical issue of the clinical syndrome in liver failure is the accumulation of toxins not cleared by the failing liver. Based on this hypothesis, the removal of lipophilic, albumin-bound substances such as bilirubin, bile acids, metabolites of aromatic amino acids, medium-chain fatty acids and cytokines should be beneficial to the clinical course of a patient in liver failure. This led to the development of artificial filtration and adsorption devices.
Hemodialysis is used for renal failure and primarily removes water soluble toxins, however it does not remove toxins bound to albumin that accumulate in liver failure.
Read more about Liver Dialysis: Liver Dialysis Prognosis/survival, Liver Dialysis Devices
Famous quotes containing the word liver:
“The menu was stewed liver and rice, fricassee of bones, and shredded dog biscuit. The dinner was greatly appreciated; the guests ate until they could eat no more, and Elisha Dyer’s dachshund so overtaxed its capacities that it fell unconscious by its plate and had to be carried home.”
—For the State of Rhode Island, U.S. public relief program (1935-1943)