Sp-Sq
- Spicket River - New Hampshire, Massachusetts
- Spirit River - Wisconsin
- Spokane River - Idaho, Washington
- Spoon River - Illinois
- Sprague River - Maine
- Sprague River - Oregon
- Spring Creek - Minnesota
- Spring Creek - North Dakota
- Spring Creek - West Virginia
- Spring River - Arkansas, Missouri
- Spring River - Missouri, Kansas, Oklahoma
- Spruce River - Wisconsin
- Squam River - New Hampshire
- Squamscott River - New Hampshire
- Squannacook River - Massachusetts
- Squaw Creek - Iowa
- Squaw Creek - Oregon
- Squirrel River - Alaska
Read more about this topic: List Of Rivers Of The United States: S