Main Inter-regional Lines
| Name | End and major calling points | Countries and regions | Category |
|---|---|---|---|
| Cross Country Route | Bristol, Birmingham, Sheffield, Leeds, York | England: East Midlands, South West, Yorkshire and the Humber, West Midlands | Main line |
| East Coast Main Line | London, Leeds, York, Newcastle, Edinburgh | England: East, East Midlands, London, North East, Yorkshire and the Humber; Scotland | High speed Main line |
| Great Eastern Main Line | London, Ipswich, Norwich | England: East, London | Main line |
| Great Western Main Line | London, Bristol, Cardiff | England: London, South East, South West; South Wales | High speed Main line |
| High Speed 1 | London, Channel Tunnel | England: East, London, South East | High speed line |
| Midland Main Line | London, Leicester, Nottingham, Sheffield, Leeds | England: East, East Midlands, London, Yorkshire and the Humber | Main line |
| West Coast Main Line | London, Birmingham, Liverpool, Manchester, Glasgow | England: London, North West, South East, West Midlands; Scotland; North Wales | High speed Main line |
Read more about this topic: List Of Railway Lines In Great Britain
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