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- Edmund Randolph (1753–1813) – Gov of Virginia, United States Attorney General, United States Secretary of State
- Peyton Randolph – 1775 President of the Continental Congress
- Clay Rapada (born 1981) – relief pitcher for the New York Yankees
- J. J. Redick § (born 1984) – shooting guard for the Orlando Magic
- Ralph Reed (born 1961) - conservative political activist, novelist
- Tim Reid (born 1944) – actor, comedian, director, WKRP in Cincinnati, Simon & Simon, Sister, Sister
- J. Sargeant Reynolds – businessman, statesman, and Virginia Lieutenant Governor
- Mark Reynolds § (born 1983) – infielder for the Baltimore Orioles
- Chris Richardson § (born 1984) – American Idol finalist
- Alex Riley-WWE Superstar
- David L. Robbins – novelist
- Tom Robbins – author, studied art at Richmond Professional Institute (now VCU) and worked for the Richmond Times Dispatch
- Pat Robertson (born 1930) – Christian televangelist and political leader
- Bill "Bojangles" Robinson§(1878–1949) – dancer
- David Robinson § (born 1965) – former NBA star
- Michael Robinson (born 1983) – running back for the Seattle Seahawks
- John Rolfe § (c. 1585–1622) – settler at Jamestown Settlement, first developer of cultivated tobacco for the European market
- Felipe Rose § – founding member of the Village People
- Bobby Ross § – American football coach
- Aaron Rouse (born 1984) – safety for the United Football League
- Eddie Royal (born 1986) – wide receiver for the Denver Broncos
- Mark Ruffalo § (born 1967) – actor, Shutter Island, Collateral, The Avengers
Read more about this topic: List Of People From Virginia