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- Jeffrey M. Lacker – chief executive of the Fifth District Federal Reserve Bank at Richmond
- Kendall Langford – defensive end for the Miami Dolphins
- Rick Langford – former MLB pitcher
- Wayne LaPierre – Executive Vice President of the National Rifle Association, author, and Second Amendment advocate
- Mat Latos – starting pitcher for the Cincinnati Reds
- Wilford Leach (1929–1988) – film and theatre director, screenwriter
- Light Horse Harry Lee (1756–1818) Prince William County; Revolutionary War hero; father of Robert E. Lee
- Jake E. Lee (born 1957) – guitarist for Ratt, Rough Cutt, Ozzy Osbourne, Badlands, and others
- Richard Henry Lee (1732–1794) Westmoreland County; presented the proposal for independence to Continental Congress in 1776
- Robert E. Lee (1807–1870) – Confederate States of America military leader, commander of Army of Northern Virginia
- William Gregory Lee – actor, Dante's Cove
- Tim Legler – ESPN NBA analyst
- Meriwether Lewis (1774–1809) – explorer with the Lewis and Clark Expedition
- Shaquan Lewis – aka "Skillz" from the Supafriendz, African-American rapper
- Sabrina Lloyd (born 1970) – actress, Sliders, Sports Night, Numb3rs
- Mike London (born 1960) – head football coach of UVA
- Hyman Isaac Long (born 18th century) - Freemason
- Javier López § (born 1977) – relief pitcher for the San Francisco Giants
- David Lowery – lead singer of Cracker and co-founder of Sound of Music Studios
- Rich Lowry (born 1968) – editor of National Review, syndicated columnist, and author
Read more about this topic: List Of People From Virginia