Athletics
- Grover Cleveland Alexander (1887–1950), Baseball Hall of Fame pitcher
- Barry Alvarez (1946–), Wisconsin Badgers football coach and athletic director
- Max Baer (1909–1959), boxer
- Brad Beckman (1964–1989), professional football player from 1988 to 1989
- Wade Boggs (1958–), professional baseball player from 1982 to 1999
- Steve Borden "Sting" (1959–), professional wrestler for CWA, UWF, NWA, WCW, WWA, and TNA
- Bob Cerv (1926–), professional baseball player from 1951 to 1962
- Joba Chamberlain (1985–), professional baseball pitcher for the New York Yankees
- Jeromey Clary (1983–), offensive tackle for the San Diego Chargers
- Bob Devaney (1915–1997), football coach for the University of Nebraska Cornhuskers
- Ted "The Million Dollar Man" DiBiase (1954–), professional wrestler
- Brian Duensing (1983–), starting pitcher for the Minnesota Twins
- Rulon Gardner (1971-), Olympic gold medalist in Greco-Roman wrestling
- Bob Gibson (1935–), Baseball Hall of Fame pitcher for the St. Louis Cardinals
- Alex Gordon (1984–), left fielder for the Kansas City Royals
- Ahman Green (1977–), football player for the Seattle Seahawks, Green Bay Packers, and Houston Texans
- Alex Henery (1987–), placekicker for the Philadelphia Eagles
- Russ Hochstein (1977–), guard for the Denver Broncos
- Jeremy Horn (1975–), mixed martial arts fighter in the Ultimate Fighting Championship
- Chris Kelsay (1979–), outside linebacker for the Buffalo Bills
- Monte Kiffin (1940–), assistant head coach for the USC Trojans
- Sam Koch (1982–), punter for Baltimore Ravens
- Manny Lawson (1984–), outside linebacker for the San Francisco 49ers
- Frank Leahy (1908–1973), football player, coach, and College Football Hall of Famer
- Sean McDermott (1974–), defensive coordinator for the Carolina Panthers
- Zach Miller (1984–), tight end for the Jacksonville Jaguars
- Gregg Olson (1966–), professional baseball pitcher
- Jed Ortmeyer (1978–), professional hockey player for the Minnesota Wild
- Tom Osborne (1937–), former football coach for the University of Nebraska Cornhuskers
- Zach Potter (born 1986), tight end for the Jacksonville Jaguars
- Ron Prince (1969–), assistant offensive line coach for the Indianapolis Colts
- James Raschke (1940–), professional wrestler
- Andy Roddick (1982–), tennis star
- Gale Sayers (1943–), Football Hall of Fame running back for the Chicago Bears
- Scott Shanle (1979– ), outside linebacker for the New Orleans Saints
- George Stone (1876–1945), Major League Baseball left fielder who was the 1906 batting champion
- Curtis Tomasevicz (1980–), 2006 U.S. Olympic bobsledder and former Nebraska Cornhuskers football player
- "Gorgeous George" Wagner (1915–1963), professional wrestler
- Dan Warthen (1952–), former MLB pitcher and current pitching coach for the New York Mets
- Danny Woodhead (1983–), running back for the New England Patriots, attended Chadron State College
Read more about this topic: List Of People From Nebraska